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Xaira Therapeutics

AI-native drug discovery with $1B+ launch — largest in biotech history

Founded2024
HQSan Francisco, CA / Seattle, WA
StagePreclinical
Total Funding$1B+
xaira.com
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Overview

Xaira Therapeutics launched in April 2024 with over $1 billion in committed funding — the largest venture-backed launch in biotech history. Co-founded by Nobel laureate David Baker and led by former Genentech CSO Marc Tessier-Lavigne, Xaira combines cutting-edge protein and antibody design AI (RFdiffusion, RFantibody) with deep drug development expertise. The company's board includes former FDA Commissioner Scott Gottlieb, Nobel laureate Carolyn Bertozzi, and former J&J CEO Alex Gorsky.

Focus areas

Antibody Design, Generative Chemistry, Structure Prediction, Foundation Models

Key models

RFdiffusion, RFantibody


Funding

$1B+

Total raised

Series A2024-04

$1B+

Led by Arch Venture Partners, Foresite Labs

Notable investors

Arch Venture Partners · Foresite Labs · F-Prime · NEA · Sequoia Capital · Lux Capital · Lightspeed Venture Partners


Technology

AI-native drug discovery platform built on frontier protein and antibody design models from David Baker's lab. RFdiffusion generates novel protein structures, and RFantibody designs antibodies de novo. The platform combines these generative AI capabilities with large-scale data generation and therapeutic product development.

Platforms & Tools
RFdiffusionRFantibodyProtein design AILarge-scale data generation

Leadership

Marc Tessier-Lavigne

CEO

Former CSO at Genentech, former President of Stanford University

David Baker

Co-Founder

Nobel Prize in Chemistry 2024, Director of Institute for Protein Design at UW


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