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Clinical Pipeline

3 articles


⚡️Boltz‑2: The Co‑Folding Model That Actually Predicts Binding Affinity
Protein Structure Prediction

⚡️Boltz‑2: The Co‑Folding Model That Actually Predicts Binding Affinity

Boltz-2, the latest wave in AI models for biology, was announced last week. It’s a leap ahead of its predecessor Boltz-1 which gave Alphafold 3 a run for its money. Where previous models are strong predictors of target structure, binding affinity...

Jun 16, 2025·5 min
The Protein Language Model: Bigger = Better?
Protein Structure Prediction

The Protein Language Model: Bigger = Better?

Exhibit A Profluent has announced their new family of foundation models for protein generation, the ProGen3 series. Whether you’re looking to understand their methods and findings, or simply curious on what the heck a protein language model is ––...

May 6, 2025·15 min
AI is becoming the lab. Expert insights from NVIDIA GTC 2025, Foundation Models for Drug Discovery, etc.
Protein Structure Prediction

AI is becoming the lab. Expert insights from NVIDIA GTC 2025, Foundation Models for Drug Discovery, etc.

Sprintome is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. From foundation models like Evo 2 and Alphafold 3 to synthetic data generation and agentic AI workflows — Next‑gen AI...

Apr 17, 2025·7 min

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